Xanthine Oxidase-Induced Inflammatory Responses in Respiratory Epithelial Cells: A Review in Immunopathology of COVID-19

• Main Authors: Irandi Putra Pratomo (Author), Dimas R. Noor (Author), Kusmardi Kusmardi (Author), Andriansjah Rukmana (Author), Rafika I. Paramita (Author), Linda Erlina (Author), Fadilah Fadilah (Author), Anggi Gayatri (Author), Magna Fitriani (Author), Tommy T. H. Purnomo (Author), Anna Ariane (Author), Rudi Heryanto (Author), Aryo Tedjo (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Xanthine oxidase (XO) is an enzyme that catalyzes the production of uric acid and superoxide radicals from purine bases: hypoxanthine and xanthine and is also expressed in respiratory epithelial cells. Uric acid, which is also considered a danger associated molecule pattern (DAMP), could trigger a s...