Concepts for New Rapid Simple HPLC Method for Quantification of Fosfomycin Trometamol in Pharmaceutical Dosage Forms with Direct UV Detection

• Egile Nagusiak: Marjan Piponski (Egilea), Tanja Bakovska Stoimenova (Egilea), Tetiana Melnyk (Egilea), Sergiy Kovalenko (Egilea), Elena Lazarevska Todevska (Egilea), Marjan Velkovski (Egilea), Sami El Deeb (Egilea), Yuriy Mysula (Egilea), Liliya Logoyda (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Two different concepts for developing direct HPLC-UV methods for quantifying fosfomycin trometamol were developed without any derivatization and modification of the analyte. In the first concept, without the use of alkylamines as ion-pairs in the mobile phase, by using cyanopropyl CN and a strong an...