Design, synthesis, and biological evaluation of novel ciprofloxacin derivatives as potential anticancer agents targeting topoisomerase II enzyme

A series of novel ciprofloxacin (CP) derivatives substituted at the N-4 position with biologically active moieties were designed and synthesised. 14 compounds were 1.02- to 8.66-fold more potent than doxorubicin against T-24 cancer cells. Ten compounds were 1.2- to 7.1-fold more potent than doxorubi...

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主要な著者: Hadeer K. Swedan (著者), Asmaa E. Kassab (著者), Ehab M. Gedawy (著者), Salwa E. Elmeligie (著者)
フォーマット: 図書
出版事項: Taylor & Francis Group, 2023-12-01T00:00:00Z.
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3rd Floor Main Library

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請求記号: A1234.567
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