Design, synthesis, and biological evaluation of novel ciprofloxacin derivatives as potential anticancer agents targeting topoisomerase II enzyme
A series of novel ciprofloxacin (CP) derivatives substituted at the N-4 position with biologically active moieties were designed and synthesised. 14 compounds were 1.02- to 8.66-fold more potent than doxorubicin against T-24 cancer cells. Ten compounds were 1.2- to 7.1-fold more potent than doxorubi...
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フォーマット: | 図書 |
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Taylor & Francis Group,
2023-12-01T00:00:00Z.
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請求記号: |
A1234.567 |
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所蔵 1 | 利用可 |