Relationship Between the High Frequency of 23S rRNA Point Mutations in Treponema Pallidum and Low Serological Response Rate to Azithromycin Treatment in China

• Main Authors: Rui-Li Zhang (Author), Qian-Qiu Wang (Author), Zhi-Ju Zheng (Author), Guo-Jun Liang (Author), Li-Jia Yang (Author), Li-Gang Yang (Author), Dong-Nu Pei (Author), Shao-Chun Lin (Author)
• Format: Book
• Published: Wolters Kluwer Health, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract. Objective:. Although azithromycin is effective against Treponema pallidum (T. pallidum), the causative agent of syphilis, recent reports indicate that the prevalence of azithromycin resistance in China is very high, which may result in the failure of treatment. In this study, we aimed to i...