Dexmedetomidine Inhibits Inflammatory Reaction in Lung Tissues of Septic Rats by Suppressing TLR4/NF-κB Pathway

• Main Authors: Yuqing Wu (Author), Yingchun Liu (Author), He Huang (Author), Yangzi Zhu (Author), Yong Zhang (Author), Fuzhao Lu (Author), Ce Zhou (Author), Li Huang (Author), Xin Li (Author), Chenghua Zhou (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dexmedetomidine has been reported to reduce mortality in septic rats. This study was designed to investigate the effects of dexmedetomidine on inflammatory reaction in lung tissues of septic rats induced by CLP. After induction of sepsis, the rats were treated with normal saline or dexmedetomidine (...