Proteasome dysfunction disrupts adipogenesis and induces inflammation via ATF3

• Hoofdauteurs: Nienke Willemsen (Auteur), Isabel Arigoni (Auteur), Maja Studencka-Turski (Auteur), Elke Krüger (Auteur), Alexander Bartelt (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2022-08-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Objective: Regulation of proteasomal activity is an essential component of cellular proteostasis and function. This is evident in patients with mutations in proteasome subunits and associated regulators, who suffer from proteasome-associated autoinflammatory syndromes (PRAAS). These patients display...