Proteasome dysfunction disrupts adipogenesis and induces inflammation via ATF3

• Egile Nagusiak: Nienke Willemsen (Egilea), Isabel Arigoni (Egilea), Maja Studencka-Turski (Egilea), Elke Krüger (Egilea), Alexander Bartelt (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2022-08-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Objective: Regulation of proteasomal activity is an essential component of cellular proteostasis and function. This is evident in patients with mutations in proteasome subunits and associated regulators, who suffer from proteasome-associated autoinflammatory syndromes (PRAAS). These patients display...