Leptomeningeal Cells Transduce Peripheral Macrophages Inflammatory Signal to Microglia in Reponse to Porphyromonas gingivalis LPS

• Päätekijät: Yicong Liu (Tekijä), Zhou Wu (Tekijä), Xinwen Zhang (Tekijä), Junjun Ni (Tekijä), Weixian Yu (Tekijä), Yanmin Zhou (Tekijä), Hiroshi Nakanishi (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Hindawi Limited, 2013-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

We report here that the leptomeningeal cells transduce inflammatory signals from peripheral macrophages to brain-resident microglia in response to Porphyromonas gingivalis (P.g.) LPS. The expression of Toll-like receptor 2 (TLR2), TLR4, TNF-α, and inducible NO synthase was mainly detected in the gin...