Mortality reduction benefits and intussusception risks of rotavirus vaccination in 135 low-income and middle-income countries: a modelling analysis of current and alternative schedules

• Main Authors: Andrew Clark, PhD (Author), Jacqueline Tate, PhD (Author), Umesh Parashar, MD (Author), Mark Jit, PhD (Author), Mateusz Hasso-Agopsowicz, PhD (Author), Nicholas Henschke, PhD (Author), Benjamin Lopman, PhD (Author), Kevin Van Zandvoort, MSc (Author), Clint Pecenka, PhD (Author), Paul Fine, PhD (Author), Colin Sanderson, PhD (Author)
• Format: Book
• Published: Elsevier, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Background: Infant rotavirus vaccines have led to substantial reductions in hospital admissions and deaths due to gastroenteritis, but some studies have reported an elevated risk of intussusception, a rare bowel disorder. This analysis aimed to provide evidence on the potential mortality re...