Caspase-1 is involved in the genesis of inflammatory hypernociception by contributing to peripheral IL-1β maturation

• Main Authors: Zamboni Dario S (Author), Verri Waldiceu A (Author), Sonego Fabiane (Author), Guerrero Ana T (Author), Souza Guilherme R (Author), Vieira Silvio M (Author), Pinto Larissa G (Author), Talbot Jhimmy (Author), Cunha Thiago M (Author), Ferreira Sergio H (Author), Cunha Fernando Q (Author)
• Format: Book
• Published: SAGE Publishing, 2010-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Caspase-1 is a cysteine protease responsible for the processing and secretion of IL-1β and IL-18, which are closely related to the induction of inflammation. However, limited evidence addresses the participation of caspase-1 in infla...