Disposition of Hexahydrocannabinol Epimers and Their Metabolites in Biological Matrices following a Single Administration of Smoked Hexahydrocannabinol: A Preliminary Study

• Main Authors: Annagiulia Di Trana (Author), Alessandro Di Giorgi (Author), Giorgia Sprega (Author), Jeremy Carlier (Author), Giorgi Kobidze (Author), Eva Montanari (Author), Omayema Taoussi (Author), Giulia Bambagiotti (Author), Maria Sofia Fede (Author), Alfredo Fabrizio Lo Faro (Author), Anastasio Tini (Author), Francesco Paolo Busardò (Author), Simona Pichini (Author)
• Format: Book
• Published: MDPI AG, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In 2023, hexahydrocannabinol (HHC) attracted the attention of international agencies due to its rapid spread in the illegal market. Although it was discovered in 1940, less is known about the pharmacology of its two naturally occurring epimers, 9(R)-HHC and 9(S)-HHC. Thus, we aimed to investigate th...