Role of OATP4C1 in Renal Handling of Remdesivir and its Nucleoside Analog GS-441524: The First Approved Drug for Patients with COVID-19

Purpose. Remdesivir and its active metabolite are predominantly eliminated via renal route; however, information regarding renal uptake transporters is limited. In the present study, the interaction of remdesivir and its nucleoside analog GS-441524 with OATP4C1 was evaluated to provide the detailed...

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Main Authors: Toshihiro Sato (Author), Masamitsu Maekawa (Author), Nariyasu Mano (Author), Takaaki Abe (Author), Hiroaki Yamaguchi (Author)
Format: Book
Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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