Vandetanib in a Child Affected by Neurofibromatosis Type 1 and Medullary Thyroid Carcinoma with Both NF1 and Homozygous RET Proto-oncogen Germ-line Mutations

• Main Authors: Begümhan Demir Gündoğan (Author), Fatih Sağcan (Author), Sevcan Tuğ Bozdoğan (Author), Yüksel Balcı (Author), Ferah Tuncel Daloğlu (Author), Elvan Cağlar Çıtak (Author)
• Format: Book
• Published: Galenos Yayincilik, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cases of neurofibromatosis type 1 (NF1)-associated medullary thyroid carcinoma (MTC) or C-cell hyperplasia are rarely associated with other endocrine tumors or cases with a multiple endocrine neoplasia type 2. In these patients, mutations were detected in the NF1 gene but no mutations were detected...