Vandetanib in a Child Affected by Neurofibromatosis Type 1 and Medullary Thyroid Carcinoma with Both NF1 and Homozygous RET Proto-oncogen Germ-line Mutations

• Auteurs principaux: Begümhan Demir Gündoğan (Auteur), Fatih Sağcan (Auteur), Sevcan Tuğ Bozdoğan (Auteur), Yüksel Balcı (Auteur), Ferah Tuncel Daloğlu (Auteur), Elvan Cağlar Çıtak (Auteur)
• Format: Livre
• Publié: Galenos Yayincilik, 2021-09-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Cases of neurofibromatosis type 1 (NF1)-associated medullary thyroid carcinoma (MTC) or C-cell hyperplasia are rarely associated with other endocrine tumors or cases with a multiple endocrine neoplasia type 2. In these patients, mutations were detected in the NF1 gene but no mutations were detected...