MEG3, as a Competing Endogenous RNA, Binds with miR-27a to Promote PHLPP2 Protein Translation and Impairs Bladder Cancer Invasion

• Main Authors: Chao Huang (Author), Xin Liao (Author), Honglei Jin (Author), Fei Xie (Author), Fuxing Zheng (Author), Jingxia Li (Author), Chenfan Zhou (Author), Guosong Jiang (Author), Xue-Ru Wu (Author), Chuanshu Huang (Author)
• Format: Book
• Published: Elsevier, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Muscle-invasive and metastatic bladder cancer have an extremely poor 5-year survival rate of 5%. In comparison, all other bladder cancers (BCs) have a 5-year survival rate of 77%. This striking contrast indicates that one of the therapeutic kernels for bladder cancer is to elucidate the molecular me...