MEG3, as a Competing Endogenous RNA, Binds with miR-27a to Promote PHLPP2 Protein Translation and Impairs Bladder Cancer Invasion

• Autores principales: Chao Huang (Autor), Xin Liao (Autor), Honglei Jin (Autor), Fei Xie (Autor), Fuxing Zheng (Autor), Jingxia Li (Autor), Chenfan Zhou (Autor), Guosong Jiang (Autor), Xue-Ru Wu (Autor), Chuanshu Huang (Autor)
• Formato: Libro
• Publicado: Elsevier, 2019-06-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Muscle-invasive and metastatic bladder cancer have an extremely poor 5-year survival rate of 5%. In comparison, all other bladder cancers (BCs) have a 5-year survival rate of 77%. This striking contrast indicates that one of the therapeutic kernels for bladder cancer is to elucidate the molecular me...