Recombinant Envelope-Proteins with Mutations in the Conserved Fusion Loop Allow Specific Serological Diagnosis of Dengue-Infections.

• Main Authors: Alexandra Rockstroh (Author), Luisa Barzon (Author), Monia Pacenti (Author), Giorgio Palù (Author), Matthias Niedrig (Author), Sebastian Ulbert (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dengue virus (DENV) is a mosquito-borne flavivirus and a major international public health concern in many tropical and sub-tropical areas worldwide. DENV is divided into four major serotypes, and infection with one serotype leads to immunity against the same, but not the other serotypes. The specif...