Cover Image

Epidermal Growth Factor Induces Vasoconstriction Through the Phosphatidylinositol 3-Kinase-Mediated Mitogen-Activated Protein Kinase Pathway in Hypertensive Rats

Abstract.: We investigated whether increased contractile responsiveness to epidermal growth factor (EGF) is associated with altered activation of mitogen-activated protein kinase (MAPK) in the aortic smooth muscle of deoxycorticosterone acetate (DOCA)-salt hypertensive rats. EGF induced contraction...

Full description

Saved in:

Bibliographic Details
Main Authors:	Kim Junghwan (Author), Lee Chang-Kwon (Author), Park Hyo-Jun (Author), Kim Hyo Jin (Author), So Hyun Ha (Author), Lee Keun Sang (Author), Lee Hwan Myung (Author), Roh Hui Yul (Author), Choi Wahn Soo (Author), Park Tae Kyu (Author), Kim Bokyung (Author)
Format:	Book
Published:	Elsevier, 2006-01-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

p38 Mitogen-Activated Protein Kinase Regulates Vasoconstriction in Spontaneously Hypertensive Rats
by: Seongchun Kwon, et al.
Published: (2004)

Endothelin-1 Induces Contraction via a Syk-Mediated p38 Mitogen-Activated Protein Kinase Pathway in Rat Aortic Smooth Muscle
by: Hwan Myung Lee, et al.
Published: (2007)

p38 Mitogen-Activated Protein Kinase Contributes to Angiotensin II-Stimulated Migration of Rat Aortic Smooth Muscle Cells
by: Hwan Myung Lee, et al.
Published: (2007)

c-Jun N-terminal Kinase Contributes to Norepinephrine-Induced Contraction Through Phosphorylation of Caldesmon in Rat Aortic Smooth Muscle
by: Youn Ri Lee, et al.
Published: (2006)

Neuroprotective effects of erythropoietin against hypoxic injury via modulation of the mitogen-activated protein kinase pathway and apoptosis
by: Ji Eun Jeong, et al.
Published: (2017)

Mitogen Activated Protein Kinases
by: Jose Lozano
Published: (2017)

Auranofin, a Gold(I)-Containing Antirheumatic Compound, Activates Keap1/Nrf2 Signaling via Rac1/iNOS Signal and Mitogen-Activated Protein Kinase Activation
by: Nam-Hoon Kim, et al.
Published: (2010)

Design, synthesis, and study of novel phenethyl-based antitumor phospholipids downregulating p38 mitogen-activated protein kinase
by: Ahmed H. E. Hassan, et al.
Published: (2023)

Class I phosphatidylinositol 3-kinase inhibitors for cancer therapy
by: Wennan Zhao, et al.
Published: (2017)

Mitogen Activated Protein Kinases Functions in Signal Transduction and Human Diseases
Published: (2020)

Cynanoside F Controls Skin Inflammation by Suppressing Mitogen-Activated Protein Kinase Activation
by: Mara Melissa Duarte Fleitas, et al.
Published: (2022)

Mucocutaneous drug reaction after treatment with Phosphatidylinositol-3-kinase inhibitor
by: Tory Starzyk, MA, et al.
Published: (2022)

Unlocking the Mechanisms of Cutaneous Adverse Drug Reactions: Activation of the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway by EGFR Inhibitors Triggers Keratinocyte Differentiation and Polarization of Epidermal Immune Responses
by: Thomas Ondet, et al.
Published: (2021)

The Role of Phosphatidylinositol-3-Kinase and AMP-Activated Kinase in the Rapid Estrogenic Attenuation of Cannabinoid-Induced Changes in Energy Homeostasis
by: Edward J. Wagner, et al.
Published: (2011)

Mitogen-activated Protein Kinases in the Development of Normal and Diseased Kidneys
by: Midori Awazu
Published: (2017)

The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection.
by: Elizabeth A Nelson, et al.
Published: (2017)

Mitigation of acetaminophen-induced liver toxicity by the novel phosphatidylinositol 3-kinase inhibitor alpelisib
by: Mohamed E. Shaker, et al.
Published: (2023)

Lidocaine intensifies the anti-osteogenic effect on inflammation-induced human dental pulp stem cells via mitogen-activated protein kinase inhibition
by: Sang-Hoon Lee, et al.
Published: (2023)

Skin Toxicities Induced by Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and their Influence on Treatment Adjustments in Lung Cancer Patients
by: Ji Su Lee, et al.
Published: (2024)

Cadmium Stimulates the Expression of Vascular Cell Adhesion Molecule-1 (VCAM-1) via p38 Mitogen-Activated Protein Kinase (MAPK) and JNK Activation in Cerebrovascular Endothelial Cells
by: Sung Lyea Park, et al.
Published: (2009)

Melatonin Regulates Chloroplast Protein Quality Control via a Mitogen-Activated Protein Kinase Signaling Pathway
by: Hyoung Yool Lee, et al.
Published: (2021)

Stress and Vascular Responses: Mitogen-Activated Protein Kinases and Activator Protein-1 as Promising Therapeutic Targets of Vascular Remodeling
by: Shokei Kim, et al.
Published: (2003)

Mitogen-Activated Protein Kinase Inhibitors and T-Cell-Dependent Immunotherapy in Cancer
by: Sandeep Kumar, et al.
Published: (2020)

Functional Roles of p38 Mitogen-Activated Protein Kinase in Macrophage-Mediated Inflammatory Responses
by: Yanyan Yang, et al.
Published: (2014)

Corrigendum: Mitigation of acetaminophen-induced liver toxicity by the novel phosphatidylinositol 3-kinase inhibitor alpelisib
by: Mohamed E. Shaker, et al.
Published: (2023)

The Phosphatidylinositol 3-Kinase/mTor Pathway as a Therapeutic Target for Brain Aging and Neurodegeneration
by: David Heras-Sandoval, et al.
Published: (2011)

Metastatic Squamous Cell Carcinoma from Lung Adenocarcinoma after Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy
by: Hyung Kyu Park, et al.
Published: (2017)

Anti-Melanogenic Effect of Dendropanax morbiferus and Its Active Components via Protein Kinase A/Cyclic Adenosine Monophosphate-Responsive Binding Protein- and p38 Mitogen-Activated Protein Kinase-Mediated Microphthalmia−Associated Transcription Factor Downregulation
by: Jung Up Park, et al.
Published: (2020)

Effect of Azelaic Acid on Psoriasis Progression Investigated Based on Phosphatidylinositol 3-Kinase (PI3K)/Protein Kinase B (AKT) Signaling Pathway
by: Li L, et al.
Published: (2022)

Mitogen-activated protein kinases in normal and (pre)neoplastic ovarian surface epithelium
by: Leung Peter CK, et al.
Published: (2003)

The case for inhibiting p38 mitogen-activated protein kinase in heart failure
by: Pelin eArabacilar, et al.
Published: (2015)

Correction: Regulation of Development and Reproduction by the Mitogen-Activated Protein Kinase Signaling Pathway.
Published: (2014)

The flavonoid hesperidin exerts anti-photoaging effect by downregulating matrix metalloproteinase (MMP)-9 expression via mitogen activated protein kinase (MAPK)-dependent signaling pathways
by: Hee Jeong Lee, et al.
Published: (2018)

Requirement of extracellular signal-regulated kinase/mitogen-activated protein kinase for long-term potentiation in adult mouse anterior cingulate cortex
by: Ren Ming, et al.
Published: (2007)

Impaired inflammatory pain and thermal hyperalgesia in mice expressing neuron-specific dominant negative mitogen activated protein kinase kinase (MEK)
by: Kaplan David, et al.
Published: (2006)

Anti-inflammatory Activity of Methylene Chloride Fraction From Glehnia littoralis Extract via Suppression of NF-κB and Mitogen-Activated Protein Kinase Activity
by: Taesook Yoon, et al.
Published: (2010)

Mechanistic analysis of endothelial lipase G promotion of the occurrence and development of cervical carcinoma by activating the phosphatidylinositol-4,5-bisphosphate 3-kinase/protein kinase B/mechanistic target of rapamycin kinase signalling pathway
by: Jing Huang, et al.
Published: (2023)

Anti-neuroinflammatory Activity of Kamebakaurin From Isodon japonicus via Inhibition of c-Jun NH2-Terminal Kinase and p38 Mitogen-Activated Protein Kinase Pathway in Activated Microglial Cells
by: Byung-Wook Kim, et al.
Published: (2011)

Inhibition of phosphatidylinositol 3-kinase by PX-866 suppresses temozolomide-induced autophagy and promotes apoptosis in glioblastoma cells
by: Bryan G. Harder, et al.
Published: (2019)

Regulation of Schistosoma mansoni development and reproduction by the mitogen-activated protein kinase signaling pathway.
by: Luiza Freire de Andrade, et al.
Published: (2014)