Sirolimus Pharmacokinetics Variability Points to the Relevance of Therapeutic Drug Monitoring in Pediatric Oncology

Sirolimus is widely used in transplantation, where its therapeutic drug monitoring (TDM) is well established. Evidence of a crucial role for sirolimus in the PI3K/AkT/mTor pathway has stimulated interest in its involvement in neoplasia, either as monotherapy or in combination with other antineoplast...

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Main Authors: Amelia-Naomi Sabo (Author), Sarah Jannier (Author), Guillaume Becker (Author), Jean-Marc Lessinger (Author), Natacha Entz-Werlé (Author), Véronique Kemmel (Author)
Format: Book
Published: MDPI AG, 2021-03-01T00:00:00Z.
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Call Number: A1234.567
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