Momelotinib: Mechanism of action, clinical, and translational science

• मुख्य लेखकों: Georgios Vlasakakis (लेखक), Michael T. McCabe (लेखक), Yu Liu Ho (लेखक), Geraldine Ferron‐Brady (लेखक), Paul Martin (लेखक), Darren Bentley (लेखक), Catherine Ellis (लेखक), Mary Antonysamy (लेखक), Sandra A. G. Visser (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2024-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Myelofibrosis is a chronic myeloproliferative disorder characterized by bone marrow fibrosis, splenomegaly, anemia, and constitutional symptoms, with a median survival of ≈6 years from diagnosis. While currently approved Janus kinase (JAK) inhibitors (ruxolitinib, fedratinib) improve spleno...