Vγ9Vδ2 T cells as a promising innovative tool for immunotherapy of hematologic malignancies

• Main Authors: Serena Meraviglia (Author), Carmela La Mendola (Author), Valentina Orlando (Author), Francesco Scarpa (Author), Giuseppe Cicero (Author), Francesco Dieli (Author)
• Format: Book
• Published: Frontiers Media S.A., 2011-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The potent anti-tumor activities of γδ T cells, their ability to produce pro-inflammatory cytokines, and their strong cytolytic activity have prompted the development of protocols in which γδ agonists or ex vivo-expanded γδ cells are administered to tumor patients. γδ T cells can be selectively acti...