Candidates for Repurposing as Anti-Virulence Agents Based on the Structural Profile Analysis of Microbial Collagenase Inhibitors

Candidates for Repurposing as Anti-Virulence Agents Based on the Structural Profile Analysis of Microbial Collagenase Inhibitors

The pharmacological inhibition of the bacterial collagenases (BC) enzymes is considered a promising strategy to block the virulence of the bacteria without targeting the selection mechanism leading to drug resistance. The chemical structures of the <i>Clostridium perfringens</i> collagen...

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Main Authors: Georgiana Nitulescu (Author), George Mihai Nitulescu (Author), Anca Zanfirescu (Author), Dragos Paul Mihai (Author), Daniela Gradinaru (Author)
Format: Book
Published: MDPI AG, 2021-12-01T00:00:00Z.
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3rd Floor Main Library

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