Morphine, Oxycodone, and Fentanyl Exhibit Different Analgesic Profiles in Mouse Pain Models#

• Main Authors: Kazuhisa Minami (Author), Minoru Hasegawa (Author), Hisanori Ito (Author), Atsushi Nakamura (Author), Takako Tomii (Author), Mitsunobu Matsumoto (Author), Satoshi Orita (Author), Syuichi Matsushima (Author), Takako Miyoshi (Author), Koichi Masuno (Author), Mikinori Torii (Author), Katsumi Koike (Author), Shinji Shimada (Author), Toshiyuki Kanemasa (Author), Tsuyoshi Kihara (Author), Minoru Narita (Author), Tsutomu Suzuki (Author), Akira Kato (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Morphine, oxycodone, and fentanyl are clinically prescribed drugs for the management of severe pain. We investigated whether these opioids possess different efficacy profiles on several types of pain in mouse pain models. When the three opioids were tested in the femur bone cancer model, all of them...