Ultrasound-Targeted Microbubble Destruction Improves the Migration and Homing of Mesenchymal Stem Cells after Myocardial Infarction by Upregulating SDF-1/CXCR4: A Pilot Study

• Main Authors: Lu Li (Author), Shengzheng Wu (Author), Zheng Liu (Author), Zhongxiong Zhuo (Author), Kaibin Tan (Author), Hongmei Xia (Author), Lisha Zhuo (Author), Xiaojun Deng (Author), Yunhua Gao (Author), Yali Xu (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mesenchymal stem cell (MSC) therapy shows considerable promise for the treatment of myocardial infarction (MI). However, the inefficient migration and homing of MSCs after systemic infusion have limited their therapeutic applications. Ultrasound-targeted microbubble destruction (UTMD) has proven to...