Mechanochemical Synthesis and Structure of the Tetrahydrate and Mesoporous Anhydrous Metforminium(2+)-<i>N</i>,<i>N</i>'-1,4-Phenylenedioxalamic Acid (1:2) Salt: The Role of Hydrogen Bonding and n→π * Charge Assisted Interactions

• Main Authors: Sayuri Chong-Canto (Author), Efrén V. García-Báez (Author), Francisco J. Martínez-Martínez (Author), Angel A. Ramos-Organillo (Author), Itzia I. Padilla-Martínez (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A new organic salt of metformin, an antidiabetic drug, and <i>N</i>,<i>N</i>'-(1,4-phenylene)dioxalamic acid, was mechanochemically synthesized, purified by crystallization from solution and characterized by single X-ray crystallography. The structure revealed a salt-typ...