Adenosine A2A Receptors Modulate Acute Injury and Neuroinflammation in Brain Ischemia

• Main Authors: Felicita Pedata (Author), Anna Maria Pugliese (Author), Elisabetta Coppi (Author), Ilaria Dettori (Author), Giovanna Maraula (Author), Lucrezia Cellai (Author), Alessia Melani (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The extracellular concentration of adenosine in the brain increases dramatically during ischemia. Adenosine A2A receptor is expressed in neurons and glial cells and in inflammatory cells (lymphocytes and granulocytes). Recently, adenosine A2A receptor emerged as a potential therapeutic attractive ta...