Surface Engineering Methods for Powder Bed Printed Tablets to Optimize External Smoothness and Facilitate the Application of Different Coatings

• 主要な著者: Khanh T. T. Nguyen (著者), Daan Zillen (著者), Franca F. M. van Heijningen (著者), Kjeld J. C. van Bommel (著者), Renz J. van Ee (著者), Henderik W. Frijlink (著者), Wouter L. J. Hinrichs (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2023-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

In a previous attempt to achieve ileo-colonic targeting of bovine intestinal alkaline phosphatase (BIAP), we applied a pH-dependent coating, the ColoPulse coating, directly on powder bed printed (PBP) tablets. However, the high surface roughness necessitated an additional sub-coating layer [Nguyen,...