Complex nature of SNP genotype effects on gene expression in primary human leucocytes

• Main Authors: Dinesen Lotte C (Author), Swertz Morris A (Author), Bruinenberg Marcel (Author), Jansen Ritsert C (Author), Trynka Gosia (Author), Heap Graham A (Author), Hunt Karen A (Author), Wijmenga Cisca (Author), vanHeel David A (Author), Franke Lude (Author)
• Format: Book
• Published: BMC, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Genome wide association studies have been hugely successful in identifying disease risk variants, yet most variants do not lead to coding changes and how variants influence biological function is usually unknown.</p> <p>M...