Metabolism and disposition of oseltamivir (OS) in rats, determined by immunohistochemistry with monospecific antibody for OS or its active metabolite oseltamivir carboxylate (OC): A possibility of transporters dividing the drugs' excretion into the bile and kidney

Abstract Among any drugs, no comparative pharmacological study on how prodrug and its active metabolite behave in animal bodies is available. Immunohistochemistry (IHCs) using newly prepared two monoclonal antibodies, AOS‐96 and AOC‐160, monospecific for oseltamivir (OS) and its metabolite oseltamiv...

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Main Authors: Kunio Fujiwara (Author), Yutaro Yamamoto (Author), Tetsuya Saita (Author), Senya Matsufuji (Author)
Format: Book
Published: Wiley, 2020-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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