Significance of Siglec‐15 expression in colorectal cancer: association with advanced disease stage and fewer tumor‐infiltrating lymphocytes

• Main Authors: Zhao Lu (Author), Pu Cheng (Author), Fei Huang (Author), Jiyun Li (Author), Bingzhi Wang (Author), Shuangmei Zou (Author), Zhaoxu Zheng (Author), Chunwei Peng (Author)
• Format: Book
• Published: Wiley, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Siglec‐15, a novel immune suppressor, is upregulated in many human cancers. The aim of this study was to explore the expression of Siglec‐15 in colorectal cancer (CRC), and investigate whether Siglec‐15 could be a potential target for cancer immunotherapy in patients with CRC. We performed...