Acteoside and ursolic acid synergistically protects H2O2-induced neurotrosis by regulation of AKT/mTOR signalling: from network pharmacology to experimental validation

• Main Authors: Yan-Jie Qu (Author), Min-Rui Ding (Author), Chao Gu (Author), Li-Min Zhang (Author), Rong-Rong Zhen (Author), Jin-Fang Chen (Author), Bing Hu (Author), Hong-Mei An (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Ursolic acid (UA) and acteoside (ATS) are important active components that have been used to treat Alzheimer's disease (AD) because of their neuroprotective effects, but the exact mechanism is still unclear.Objective Network pharmacology was used to explore the mechanism of UA + ATS in...