Zinc oxide nanoparticles and spironolactone-enhanced Nrf2/HO-1 pathway and inhibited Wnt/β-catenin pathway in adenine-induced nephrotoxicity in rats

• প্রধান লেখক: Amira Awadalla (লেখক), Eman T. Hamam (লেখক), Fardous F. El-Senduny (লেখক), Nisreen Mansour Omar (লেখক), Mohamed R. Mahdi (লেখক), Nashwa Barakat (লেখক), Omar A. Ammar (লেখক), Abdelaziz M. Hussein (লেখক), Ahmed A. Shokeir (লেখক), Salma M. Khirallah (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Objective To investigate the renoprotective, the antioxidant, and the anti-inflammatory impact of a combination of SPL and ZnO-NPs to combat against chronic kidney disease (CKD).Methods In total, 50 males of rats were distributed into 5 groups (10 rats each); normal group, adenine sulfate (0.25% in...