DNMT3a-mediated methylation of PSTPIP2 enhances inflammation in alcohol-induced liver injury via regulating STAT1 and NF-κB pathway

• Main Authors: Jie-Jie Xu (Author), Lin Zhu (Author), Hai-Di Li (Author), Xiao-Sa Du (Author), Juan-Juan Li (Author), Na-Na Yin (Author), Xiao-Ming Meng (Author), Cheng Huang (Author), Jun Li (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alcohol-induced liver injury (ALI) is associated with inflammatory responses regulated by macrophages. Activation of macrophages plays a crucial role in ALI while DNA methylation-regulated gene silencing is associated with inflammation processes in macrophages. Proline-Serine-Threonine Phosphatase I...