Potential Clinical Implications of the Urotensin II Receptor Antagonists
Urotensin-II (UII), which binds to its receptor UT, plays an important role in the heart, kidneys, pancreas, adrenal gland and CNS. In the vasculature, it acts as a potent endothelium-independent vasoconstrictor and endothelium-dependent vasodilator. In disease states, this constriction-dilation equ...
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Frontiers Media S.A.,
2011-07-01T00:00:00Z.
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