Evolution of mutations in the ftsI gene leading to amino acid substitutions in PBP3 in Haemophilus influenzae strains under the selective pressure of ampicillin and cefuroxime

Background: Aminopenicillins are recommended agents for non-invasive Haemophilus influenzae infections. One of the mechanisms of resistance to β-lactams is the alteration of the transpeptidase region of penicillin binding protein 3 (PBP3) which is caused by mutations in the ftsI gene. It was shown t...

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Main Authors: Vladislav Jakubu (Author), Iveta Vrbova (Author), Ibrahim Bitar (Author), Marketa Cechova (Author), Lucia Malisova (Author), Helena Zemlickova (Author)
Format: Book
Published: Elsevier, 2024-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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