Evolution of mutations in the ftsI gene leading to amino acid substitutions in PBP3 in Haemophilus influenzae strains under the selective pressure of ampicillin and cefuroxime
Background: Aminopenicillins are recommended agents for non-invasive Haemophilus influenzae infections. One of the mechanisms of resistance to β-lactams is the alteration of the transpeptidase region of penicillin binding protein 3 (PBP3) which is caused by mutations in the ftsI gene. It was shown t...
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Main Authors: | Vladislav Jakubu (Author), Iveta Vrbova (Author), Ibrahim Bitar (Author), Marketa Cechova (Author), Lucia Malisova (Author), Helena Zemlickova (Author) |
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Format: | Book |
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Elsevier,
2024-09-01T00:00:00Z.
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