Multiple Effects of Ascorbic Acid against Chronic Diseases: Updated Evidence from Preclinical and Clinical Studies

• Main Authors: Massimiliano Berretta (Author), Vincenzo Quagliariello (Author), Nicola Maurea (Author), Raffaele Di Francia (Author), Saman Sharifi (Author), Gaetano Facchini (Author), Luca Rinaldi (Author), Michela Piezzo (Author), Ceccarelli Manuela (Author), Giuseppe Nunnari (Author), Monica Montopoli (Author)
• Format: Book
• Published: MDPI AG, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Severe disease commonly manifests as a systemic inflammatory process. Inflammation is associated withthe enhanced production of reactive oxygen and nitrogen species and with a marked reduction in the plasma concentrations of protective antioxidant molecules. This imbalance gives rise to oxidative st...