Rapamycin treatment increases survival, autophagy biomarkers and expression of the anti‐aging klotho protein in elderly mice

• Main Authors: Kitti Szőke (Author), Beáta Bódi (Author), Zoltán Hendrik (Author), Attila Czompa (Author), Alexandra Gyöngyösi (Author), Donald David Haines (Author), Zoltán Papp (Author), Árpád Tósaki (Author), István Lekli (Author)
• Format: Book
• Published: Wiley, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Previous investigations have demonstrated that treatment of animals with rapamycin increases levels of autophagy, which is a process by which cells degrade intracellular detritus, thus suppressing the emergence of senescent cells, whose pro‐inflammatory properties, are primary drivers of ag...