Rapamycin treatment increases survival, autophagy biomarkers and expression of the anti‐aging klotho protein in elderly mice

• Päätekijät: Kitti Szőke (Tekijä), Beáta Bódi (Tekijä), Zoltán Hendrik (Tekijä), Attila Czompa (Tekijä), Alexandra Gyöngyösi (Tekijä), Donald David Haines (Tekijä), Zoltán Papp (Tekijä), Árpád Tósaki (Tekijä), István Lekli (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Wiley, 2023-06-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Previous investigations have demonstrated that treatment of animals with rapamycin increases levels of autophagy, which is a process by which cells degrade intracellular detritus, thus suppressing the emergence of senescent cells, whose pro‐inflammatory properties, are primary drivers of ag...