Genetically-encoded tools for cAMP probing and modulation in living systems.

• Main Authors: Valeriy M Paramonov (Author), Veronika eMamaeva (Author), Cecilia eSahlgren (Author), Adolfo eRivero-Muller (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Intracellular 3'-5'-cyclic adenosine monophosphate (cAMP) is one of the principal second messengers downstream of a manifold of signal transduction pathways, including the ones triggered by G protein-coupled receptors. Not surprisingly, biochemical assays for cAMP have been instrumental fo...