Synthesis, in silico analysis and antidepressant activity of 1,3,4-oxadiazole derivatives

• Main Authors: Banylla Felicity Dkhar Gatphoh (Author), Natasha Naval Aggarwal (Author), S. Madan Kumar (Author), M. Vijay Kumar (Author), B. C. Revanasiddappa (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The compounds 1,3,4-oxadiazole derivatives (1-8) were synthesized by the cyclization of 4-hydroxy benzhydrazide (1) with various substituted aroma-tic aldehydes (2) using FeCl3 as catalyst and methanol as a solvent medium. The structures of the newly synthesized compounds were assigned based on FT-I...