Diabetes Attenuates the Contribution of Endogenous Nitric Oxide but Not Nitroxyl to Endothelium Dependent Relaxation of Rat Carotid Arteries

• Main Authors: Jasmin Chendi Li (Author), Anida Velagic (Author), Cheng Xue Qin (Author), Mandy Li (Author), Chen Huei Leo (Author), Barbara K. Kemp-Harper (Author), Rebecca H. Ritchie (Author), Owen L. Woodman (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction:Endothelial dysfunction is a major risk factor for several of the vascular complications of diabetes, including ischemic stroke. Nitroxyl (HNO), the one electron reduced and protonated form of nitric oxide (NO•), is resistant to scavenging by superoxide, but the role of HNO in diabetes...