A mouse model of hypoplastic left heart syndrome demonstrating left heart hypoplasia and retrograde aortic arch flow

• Hoofdauteurs: Anum Rahman (Auteur), Taylor DeYoung (Auteur), Lindsay S. Cahill (Auteur), Yohan Yee (Auteur), Sarah K. Debebe (Auteur), Owen Botelho (Auteur), Mike Seed (Auteur), Rajiv R. Chaturvedi (Auteur), John G. Sled (Auteur)
• Formaat: Boek
• Gepubliceerd in: The Company of Biologists, 2021-11-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

In hypoplastic left heart syndrome (HLHS), the mechanisms leading to left heart hypoplasia and their associated fetal abnormalities are largely unknown. Current animal models have limited utility in resolving these questions as they either do not fully reproduce the cardiac phenotype, do not survive...