Inflammatory macrophages interrupt osteocyte maturation and mineralization via regulating the Notch signaling pathway

• Autors principals: Shengfang Wang (Autor), Lan Xiao (Autor), Indira Prasadam (Autor), Ross Crawford (Autor), Yinghong Zhou (Autor), Yin Xiao (Autor)
• Format: Llibre
• Publicat: BMC, 2022-09-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Abstract Background It is well-known that both macrophages and osteocytes are critical regulators of osteogenesis and osteoclastogenesis, yet there is limited understanding of the macrophage-osteocyte interaction, and how their crosstalk could affect bone homeostasis and mineralization. This researc...