Inflammatory macrophages interrupt osteocyte maturation and mineralization via regulating the Notch signaling pathway

• Main Authors: Shengfang Wang (Author), Lan Xiao (Author), Indira Prasadam (Author), Ross Crawford (Author), Yinghong Zhou (Author), Yin Xiao (Author)
• Format: Book
• Published: BMC, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background It is well-known that both macrophages and osteocytes are critical regulators of osteogenesis and osteoclastogenesis, yet there is limited understanding of the macrophage-osteocyte interaction, and how their crosstalk could affect bone homeostasis and mineralization. This researc...