Anakinra Therapy for Non-cancer Inflammatory Diseases
Interleukin-1 (IL-1) is the prototypical inflammatory cytokine: two distinct ligands (IL-1α and IL-1β) bind the IL-1 type 1 receptor (IL-1R1) and induce a myriad of secondary inflammatory mediators, including prostaglandins, cytokines, and chemokines. IL-1α is constitutively present in endothelial a...
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Frontiers Media S.A.,
2018-11-01T00:00:00Z.
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A1234.567 |
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