Anakinra Therapy for Non-cancer Inflammatory Diseases

Interleukin-1 (IL-1) is the prototypical inflammatory cytokine: two distinct ligands (IL-1α and IL-1β) bind the IL-1 type 1 receptor (IL-1R1) and induce a myriad of secondary inflammatory mediators, including prostaglandins, cytokines, and chemokines. IL-1α is constitutively present in endothelial a...

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Main Authors: Giulio Cavalli (Author), Charles A. Dinarello (Author)
格式: 圖書
出版: Frontiers Media S.A., 2018-11-01T00:00:00Z.
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索引號: A1234.567
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