Effect of standard dose paracetamol versus placebo as antipyretic therapy on liver injury in adult dengue infection: a multicentre randomised controlled trial

• Main Authors: Vasin Vasikasin, MD (Author), Thanawith Rojdumrongrattana, MD (Author), Worayon Chuerboonchai, MD (Author), Thanawhan Siriwiwattana, MD (Author), Wittaya Thongtaeparak, MD (Author), Suchada Niyasom, MD (Author), Nawarat Lertliewtrakool, MD (Author), Sitawee Jitsiri, MD (Author), Dhitiwat Changpradub, MD (Author)
• Format: Book
• Published: Elsevier, 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Background: Dengue is a common cause of acute liver failure in tropical countries. Paracetamol is the recommended antipyretic for dengue. Related observational studies in dengue have suggested that excessive paracetamol intake is related to hepatic injury. We aimed to evaluate whether stand...