Discovery of a Novel MyD88 Inhibitor M20 and Its Protection Against Sepsis-Mediated Acute Lung Injury

• Päätekijät: Jiali Song (Tekijä), Daoxing Chen (Tekijä), Yingqiao Pan (Tekijä), Xueqin Shi (Tekijä), Qian Liu (Tekijä), Xiaoyao Lu (Tekijä), Ximing Xu (Tekijä), Gaozhi Chen (Tekijä), Yuepiao Cai (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Myeloid differentiation factor 88 (MyD88) is a hub protein in the Toll-like receptor signaling pathway, which acts as a master switch for numerous inflammatory diseases, including acute lung injury (ALI). Although this protein is considered as a crucial therapeutic target, there are currently no cli...