Multi‐compartment metabolomics and metagenomics reveal major hepatic and intestinal disturbances in cancer cachectic mice

• Main Authors: Sarah A. Pötgens (Author), Morgane M. Thibaut (Author), Nicolas Joudiou (Author), Martina Sboarina (Author), Audrey M. Neyrinck (Author), Patrice D. Cani (Author), Sandrine P. Claus (Author), Nathalie M. Delzenne (Author), Laure B. Bindels (Author)
• Format: Book
• Published: Wiley, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cancer cachexia is a multifactorial syndrome characterized by multiple metabolic dysfunctions. Besides the muscle, other organs such as the liver and the gut microbiota may also contribute to this syndrome. Indeed, the gut microbiota, an important regulator of the host metabolism...