Aloin Regulates Matrix Metabolism and Apoptosis in Human Nucleus Pulposus Cells via the TAK1/NF-κB/NLRP3 Signaling Pathway

• Main Authors: Taiqiu Chen (Author), Pengfei Li (Author), Jincheng Qiu (Author), Wenjun Hu (Author), Shaoguang Li (Author), Huihong Shi (Author), Xianjian Qiu (Author), Dongsheng Huang (Author), Wenjie Gao (Author), Anjing Liang (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Intervertebral disc degeneration (IDD) is a degenerative disease that is characterized by decreased matrix synthesis and extra degradation, nucleus pulposus cells (NPCs) apoptosis, and infiltration of inflammatory factors. Aloin, a colored compound from aloe plants, has been shown to be effective ag...