Discovery of GluN2A subtype-selective N-methyl-d-aspartate (NMDA) receptor ligands

• Main Authors: Liyang Jiang (Author), Na Liu (Author), Fabao Zhao (Author), Boshi Huang (Author), Dongwei Kang (Author), Peng Zhan (Author), Xinyong Liu (Author)
• Format: Book
• Published: Elsevier, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The N-methyl-d-aspartate (NMDA) receptors, which belong to the ionotropic Glutamate receptors, constitute a family of ligand-gated ion channels. Within the various subtypes of NMDA receptors, the GluN1/2A subtype plays a significant role in central nervous system (CNS) disorders. The present article...