Asymmetric Phenyl Substitution: An Effective Strategy to Enhance the Photosensitizing Potential of Curcuminoids

• Главные авторы: Guglielmo Vesco (Автор), Martino Brambati (Автор), Luca Scapinello (Автор), Andrea Penoni (Автор), Massimo Mella (Автор), Màr Masson (Автор), Vivek Gaware (Автор), Angelo Maspero (Автор), Luca Nardo (Автор)
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• Опубликовано: MDPI AG, 2022-07-01T00:00:00Z.
• Предметы: article
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Curcumin has been demonstrated to exhibit photosensitized bactericidal activity. However, the full exploitation of curcumin as a photo-pharmaceutical active principle is hindered by fast deactivation of the excited state through the transfer of the enol proton to the keto oxygen. Introducing an asym...