Asymmetric Phenyl Substitution: An Effective Strategy to Enhance the Photosensitizing Potential of Curcuminoids

• Main Authors: Guglielmo Vesco (Author), Martino Brambati (Author), Luca Scapinello (Author), Andrea Penoni (Author), Massimo Mella (Author), Màr Masson (Author), Vivek Gaware (Author), Angelo Maspero (Author), Luca Nardo (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Curcumin has been demonstrated to exhibit photosensitized bactericidal activity. However, the full exploitation of curcumin as a photo-pharmaceutical active principle is hindered by fast deactivation of the excited state through the transfer of the enol proton to the keto oxygen. Introducing an asym...