Microinjection of Orexin-A into the Locus Coeruleus Area Induces Morphine Withdrawal Behaviors in Morphine Independent Rats

Introduction: Orexin neuropeptide has a role in opioid withdrawal behaviors. Orexin-expressing neurons that are present in the hypothalamic nuclei send dense projections to the Locus Coeruleus (LC). Withdrawal syndrome is temporally associated with hyperactivity of LC neurons. LC neurons do not show...

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Main Authors: Hosin Azizi (Author), Atefeh Hadian (Author), Saeed Semnanian (Author)
Format: Book
Published: Drug Control Headquarters, Research and Education Office, 2012-02-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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