Development of a Hospital Compounded, Taste-Masked, Temozolomide Oral Suspension and 5-Year Real-Life Experience in Treating Paediatric Patients

• Main Authors: Maxime Annereau (Author), Mélanie Hinterlang (Author), Hugues Bienayme (Author), Gilles Vassal (Author), Antoine Pinon (Author), Mathieu Schmitt (Author), Lucas Denis (Author), Caroline Lemarchand (Author), Laurent Martin (Author), François Lemare (Author), Samuel Abbou (Author), Jérémy Bastid (Author), Lionel Tortolano (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The development of oral pediatric forms by pharmaceutical companies is still insufficient. In fact, many drugs used in paediatric oncology, such as temozolomide, are not labeled and adapted for paediatric use. Temozolomide (TMZ) is an alkylating agent used as the standard of care for many adult and...